Introduction to Bioinformatics: CMSC54610-1, Spring quarter 2006.

Term paper

• Outline and annotated reference list due week 6 (I will give you feedback by week 7)
• Final paper due week 10
• You are to support the claim that shotgun sequencing is a reliable way to sequence a genome.
  • Review the history of how and where the idea of shotgun sequencing was presented
  • Who was for it and who was against it?
  • Review the BAC to BAC approach and compare and contrast it with the shotgun approach.
  • Who was involved in the final assembly process?
  • Why do we think they got the right answer?
• Here are some Frequently Asked Questions about the term paper.
• Here is the combined list of references for the term paper.