Introduction to Bioinformatics: CMSC54610-1, Winter Quarter 2007.

Homework 6 problems:

• 6.2 (hint: see table 6.2)
• 6.4
• 6.6
• 6.10
• Determine the efficiency of the DNA representation of proteins, as follows.
  • Determine the number of each type of atom in the four bases A,C,T,G and the methylated C, and compute a score by weighting each atom by its atomic number (H=1,C=6,N=7,O=8,P=15).
  • Compute the corresponding score for each amino acid
  • Compute the ratios of the scores for each amino acid and its corresponding DNA codons
  • Be sure to include the common elements of both the DNA (Figure 1.2) and the protein backbone (Figure 1.5a). Rembember that a ring means there are C(H) groups at each vertex.
  • Hint: you may want to write a bit of computer code to do this. Just count the atoms by hand and input a table for the parts that vary.

Back to Lecture 8: Genomics and Gene Recognition